Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953993 | 0.89 | HTR1A (0.44) | HTR1ALIPECARM1PRMT6PRMT8 | |
| SCHEMBL29951056 | 0.87 | HTR1A (0.43) | HTR1ALIPECARM1PRMT6PRMT8 | |
| SCHEMBL29955252 | 0.80 | HTR1A (0.36) | HTR1ACARM1PRMT6NAAA | |
| SCHEMBL26036150 | 0.77 | HTR1A (0.41) | HTR1ACARM1PRMT6PRMT8NAAA | |
| SCHEMBL29957230 | 0.75 | DRD4 (0.41) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL28983761 | 0.74 | IDO1 (0.39) | LIPEALDH1A1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL30396772 | 0.74 | IDO1 (0.39) | LIPEALDH1A1TDP1SMN1; SMN2KMT2A | |
| SCHEMBL13003371 | 0.72 | GRM2 (0.42) | HTR1ACARM1PRMT6PRMT8ALDH1A1 | |
| SCHEMBL29951134 | 0.71 | HTR2C (0.36) | LIPEMGLLSLC6A4HTR2A | |
| SCHEMBL15725321 | 0.71 | HTR1A (0.37) | HTR1ACARM1PRMT6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |