Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955163 | 0.85 | FGFR1 (0.47) | ADORA2AADORA1ALOX5APFEN1MAP4K4 | |
| SCHEMBL29952599 | 0.83 | ERN1 (0.52) | ERN1CHEK2DYRK1AALDH1A1 | |
| SCHEMBL2562642 | 0.82 | ALOX5AP (0.44) | ADORA1ALOX5APFEN1ABL1MAPT | |
| SCHEMBL2562852 | 0.81 | FEN1 (0.56) | ALOX5APFEN1MAP4K4 | |
| SCHEMBL31195690 | 0.78 | ERN1 (0.53) | ERN1AURKBINCENPPDE3BPDE3A | |
| SCHEMBL2552689 | 0.75 | ALOX5AP (0.42) | CHEK2ALOX5APFEN1AURKBDYRK1A | |
| SCHEMBL2555064 | 0.75 | ALOX5AP (0.45) | ALOX5APFEN1ABL1CCNT1CDK9 | |
| SCHEMBL2558043 | 0.72 | ALOX5AP (0.53) | ADORA2AADORA1ALOX5APFEN1MAPT | |
| SCHEMBL30745188 | 0.72 | ERN1 (0.66) | ERN1PDE3BPDE3AMAPTPIK3CA | |
| SCHEMBL14840544 | 0.72 | ERN1 (0.47) | ERN1MAPTALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |