Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955163 | 0.84 | FGFR1 (0.47) | MEN1 | |
| SCHEMBL29953780 | 0.83 | ERN1 (0.42) | ERN1DYRK1ACHEK2ALDH1A1 | |
| SCHEMBL2552689 | 0.78 | ALOX5AP (0.42) | DYRK1AMEN1CHEK2 | |
| SCHEMBL16835900 | 0.76 | TDO2 (0.47) | ERN1CYP2A6CYP3A4CYP2E1CYP2C9 | |
| SCHEMBL16826222 | 0.76 | CYP2A6 (0.50) | CYP2A6CYP3A4CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL28494615 | 0.76 | KMO (0.49) | DYRK1ADYRK1BMKNK1MKNK2MEN1 | |
| SCHEMBL2562642 | 0.75 | ALOX5AP (0.44) | CYP3A4TDO2MEN1ALDH1A1CYP1A2 | |
| SCHEMBL1802008 | 0.75 | ERN1 (0.59) | ERN1CYP2A6CYP3A4CYP2E1CYP2C9 | |
| SCHEMBL2558043 | 0.74 | ALOX5AP (0.53) | MEN1ALDH1A1 | |
| SCHEMBL17009195 | 0.74 | ERN1 (0.54) | ERN1CYP2A6CYP3A4CYP2E1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |