Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15760086 | 1.00 | ERN1 (0.36) | ERN1ALDH1A1L3MBTL1KDM4EPTGS2 | |
| SCHEMBL21484861 | 0.80 | KDM4E (0.46) | ERN1ALDH1A1KDM4EPTGS2RAB9A | |
| SCHEMBL29954177 | 0.80 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1SMN1; SMN2POLBCASP6 | |
| SCHEMBL30013048 | 0.80 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1SMN1; SMN2POLBCASP6 | |
| SCHEMBL31002342 | 0.77 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1SMN1; SMN2POLBCASP6 | |
| SCHEMBL359521 | 0.77 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1SMN1; SMN2POLBCASP6 | |
| SCHEMBL335669 | 0.77 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2PTGS1 | |
| SCHEMBL875527 | 0.77 | POLB (0.38) | ALDH1A1L3MBTL1SMN1; SMN2NFE2L2POLB | |
| SCHEMBL4325787 | 0.77 | ALDH1A1 (0.43) | ERN1ALDH1A1L3MBTL1KDM4EPTGS2 | |
| SCHEMBL30361044 | 0.77 | POLB (0.38) | ALDH1A1L3MBTL1SMN1; SMN2NFE2L2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |