Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.92 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.92 |
| ▸ | TSHR | P16473 | 4/20 | 0.85 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.85 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.85 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.65 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.62 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.61 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 5/20 | 0.61 |
| ▸ | PPARD | Q03181 | 5/20 | 0.61 |
| ▸ | PPARA | Q07869 | 5/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27489615 | 1.00 | LMNA (0.92) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL1235934 | 1.00 | LMNA (0.92) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Sebacic Acid SCHEMBL753778 | 0.96 | TSHR (0.92) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Glutarate SCHEMBL1389252 | 0.96 | TSHR (0.92) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL28811844 | 0.96 | LMNA (0.85) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Azelaic Acid SCHEMBL11520276 | 0.96 | TSHR (0.92) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Sebacic Acid SCHEMBL7623529 | 0.96 | TSHR (0.92) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL10002678 | 0.96 | LMNA (0.85) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL2333828 | 0.96 | LMNA (0.85) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL2480632 | 0.96 | LMNA (0.85) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044062-A1 | THERMOPLASTIC PARTICULATES AND METHOD TO MAKE THEM | Jabil Inc. (US) | 2024-02-29 | — | — | WO | claimed |
| US-10312517-B2 | In situ formation of sulfur particles using organic acids in the presence of polymer functionalized carbon | TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) | 2019-06-04 | — | — | US | claimed |
| US-20180123133-A1 | IN SITU FORMATION OF SULFUR PARTICLES USING ORGANIC ACIDS IN THE PRESENCE OF POLYMER FUNCTIONALIZED CARBON | TOYOTA MOTOR ENGINEERING & MANUFACTURING NORTH AMERICA, INC. (US) | 2018-05-03 | — | — | US | claimed |
| US-6545162-B1 | Solid phase biosynthesis of viricide antibiotic | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-04-08 | — | — | US | claimed |
| WO-1995023209-A1 | BLEACHING AGENT | EKA CHEMICALS AB (SE) | 1995-08-31 | — | — | WO | claimed |
| US-5338465-A | Water soluble polymer and crosslinking/retardant system of chromium complexed with organic acid, additional different acid | ENIRICERCHE S.P.A. (IT) | 1994-08-16 | — | — | US | claimed |
| US-4716153-A | STABILIZER AND DISSOLUTION PROMOTER | TOYO JOZO COMPANY, LTD. (JP) | 1987-12-29 | — | — | US | claimed |
| WO-2024120824-A1 | A METALLIC EFFECT COATING COMPOSITION AND ITS APPLICATIONS THEREOF | BASF COATINGS GMBH (DE) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024044062-A1 | THERMOPLASTIC PARTICULATES AND METHOD TO MAKE THEM | Jabil Inc. (US) | 2024-02-29 | — | — | WO | disclosed |
| CN-113754530-B | Method for purifying adipic acid | 中国石油化工股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-115433508-A | Single-component high-strength elastic coating and preparation method and application thereof | 天津森聚柯密封涂层材料有限公司 | 2022-12-06 | — | — | CN | disclosed |
| WO-2022247786-A1 | ACID SALT OF CRYSTALLINE CSF-1R INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |
| CN-115386287-A | Weather-resistant high-strength elastic coating and preparation method and application thereof | 天津森聚柯密封涂层材料有限公司 | 2022-11-25 | — | — | CN | disclosed |
| US-4794127-A | OPENED CELL FOAMS | THE DOW CHEMICAL COMPANY (US) | 1988-12-27 | — | — | US | disclosed |
| EP-0103099-B1 | BETA-HYDROXYCYCLOPENTYLPEROXIDE COMPOUNDS AND THE USE THEREOF | NIPPON OIL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| US-4587057-A | &NTERMEDIATES FOR GLUTARALDEHYDE PRODUCTION | NIPPON OIL CO., LTD. (JP) | 1986-05-06 | — | — | US | disclosed |
| EP-0103099-A2 | Beta-hydroxycyclopentylperoxide compounds and the use thereof | NIPPON OIL CO. LTD. (JP) | 1984-03-21 | — | — | EP | disclosed |
| EP-0002598-A1 | Process for the purification of alkane dicarboxylic acids having at least 4 carbon atoms | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-06-27 | — | — | EP | disclosed |
| US-4064086-A | SPIROLACTONES | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |
| US-3968135-A | Chromium salt catalysts | AEROJET-GENERAL CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |