Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25707523 | 0.79 | HTT (0.35) | HTTHSD17B10P2RX7MGLLCYP2C19 | |
| SCHEMBL29952041 | 0.79 | HTT (0.35) | HTTHSD17B10MGLLDYRK1A | |
| SCHEMBL29955831 | 0.79 | HTT (0.35) | HTTHSD17B10P2RX7MGLLCYP2C19 | |
| SCHEMBL30050607 | 0.79 | HTT (0.35) | HTTHSD17B10P2RX7MGLLDYRK1A | |
| SCHEMBL29951895 | 0.78 | HTT (0.41) | HTTHSD17B10MGLLDYRK1A | |
| SCHEMBL29954197 | 0.75 | DYRK1A (0.38) | HTTHSD17B10DYRK1A | |
| SCHEMBL15330051 | 0.75 | GLP1R (0.33) | — | |
| SCHEMBL23508729 | 0.75 | SMN1; SMN2 (0.38) | HTTHSD17B10PTPN11P2RX7DYRK1A | |
| SCHEMBL21197638 | 0.75 | NAPRT (0.31) | — | |
| SCHEMBL29957513 | 0.74 | NOTUM (0.32) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |