Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25707523 | 1.00 | HTT (0.35) | HTTHSD17B10MGLLP2RX7DYRK1A | |
| SCHEMBL2563010 | 0.82 | HTT (0.32) | HTTHSD17B10 | |
| SCHEMBL30050607 | 0.81 | HTT (0.35) | HTTHSD17B10MGLLP2RX7DYRK1A | |
| SCHEMBL29952041 | 0.81 | HTT (0.35) | HTTHSD17B10MGLLDYRK1A | |
| SCHEMBL29953887 | 0.79 | HTT (0.34) | HTTHSD17B10MGLLP2RX7DYRK1A | |
| SCHEMBL29951895 | 0.79 | HTT (0.41) | HTTHSD17B10MGLLDYRK1A | |
| SCHEMBL29954197 | 0.77 | DYRK1A (0.38) | HTTHSD17B10DYRK1A | |
| SCHEMBL29954252 | 0.76 | NOS2 (0.39) | — | |
| SCHEMBL1191847 | 0.75 | NAPRT (0.32) | — | |
| SCHEMBL29957947 | 0.75 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |