Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957715 | 0.88 | KDM4E (0.43) | KDM4ERECQLMAPTL3MBTL1KMT2A | |
| SCHEMBL29952778 | 0.86 | RECQL (0.42) | KDM4ERECQLMAPTL3MBTL1KMT2A | |
| SCHEMBL15329817 | 0.79 | RECQL (0.37) | KDM4ERECQLMAPTL3MBTL1KMT2A | |
| SCHEMBL29957444 | 0.77 | MEN1 (0.44) | KDM4ERECQLMAPTL3MBTL1KMT2A | |
| SCHEMBL2559921 | 0.77 | RECQL (0.44) | KDM4ERECQLMAPTKMT2ALMNA | |
| SCHEMBL15330763 | 0.77 | RECQL (0.40) | RECQLMAPTL3MBTL1KMT2ALMNA | |
| SCHEMBL2076094 | 0.75 | RECQL (0.53) | RECQLMAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL29951688 | 0.75 | SMN1; SMN2 (0.33) | MAPTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29950537 | 0.75 | MEN1 (0.47) | RECQLMAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL15331029 | 0.75 | RECQL (0.41) | RECQLMAPTL3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |