Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953907 | 0.88 | KDM4E (0.43) | KDM4ERECQLMAPTLMNASMN1; SMN2 | |
| SCHEMBL29952778 | 0.84 | RECQL (0.42) | KDM4ERECQLMAPTLMNASMN1; SMN2 | |
| SCHEMBL29957444 | 0.78 | MEN1 (0.44) | KDM4ERECQLMAPTLMNASMN1; SMN2 | |
| SCHEMBL15329817 | 0.77 | RECQL (0.37) | KDM4ERECQLMAPTLMNASMN1; SMN2 | |
| SCHEMBL2076094 | 0.76 | RECQL (0.53) | RECQLMAPTLMNASMN1; SMN2PTGS2 | |
| SCHEMBL29950537 | 0.76 | MEN1 (0.47) | RECQLMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL2559921 | 0.76 | RECQL (0.44) | KDM4ERECQLMAPTLMNASMN1; SMN2 | |
| SCHEMBL15330763 | 0.75 | RECQL (0.40) | RECQLMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL29951859 | 0.74 | SMN1; SMN2 (0.34) | SMN1; SMN2L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29955244 | 0.74 | MEN1 (0.49) | KDM4ERECQLMAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |