Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332886 | 0.91 | RXFP1 (0.52) | RXFP1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL29953174 | 0.86 | CYP1A2 (0.57) | RXFP1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL25640341 | 0.79 | KDM4E (0.61) | RXFP1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL17864792 | 0.78 | KDM4E (0.63) | RXFP1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9357053 | 0.78 | CHRM2 (0.71) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL348999 | 0.77 | MAPT (0.64) | RXFP1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL17982837 | 0.77 | RXFP1 (0.55) | RXFP1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL2559982 | 0.74 | RXFP1 (0.62) | RXFP1ALDH1A1SMN1; SMN2MEN1POLB | |
| SCHEMBL15330421 | 0.74 | RXFP1 (0.52) | RXFP1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL5111329 | 0.73 | POLB (0.48) | ALDH1A1KDM4ELMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |