Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18837358 | 0.83 | MAP2K4 (0.40) | MAP2K4RORCKDM4EALDH1A1NR1H2 | |
| SCHEMBL16724831 | 0.82 | MAP2K4 (0.39) | MAP2K4KDM4EALDH1A1NR1H2BCHE | |
| SCHEMBL31190600 | 0.82 | MAP2K4 (0.39) | MAP2K4RORCKDM4EALDH1A1NR1H2 | |
| SCHEMBL31190710 | 0.82 | MAP2K4 (0.41) | MAP2K4RORCKDM4EALDH1A1NR1H2 | |
| SCHEMBL5951848 | 0.82 | MAP2K4 (0.41) | MAP2K4RORCKDM4EALDH1A1NR1H2 | |
| SCHEMBL5951579 | 0.82 | MAP2K4 (0.39) | MAP2K4RORCKDM4EALDH1A1NR1H2 | |
| SCHEMBL29955669 | 0.80 | MAP2K4 (0.34) | MAP2K4BCHEGABRG2GABRB3GABRA5 | |
| SCHEMBL31190764 | 0.79 | MAP2K4 (0.39) | MAP2K4RORCKDM4EALDH1A1NR1H2 | |
| SCHEMBL31190618 | 0.78 | MET (0.38) | MAP2K4KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL3598244 | 0.78 | MET (0.38) | MAP2K4KDM4EALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220747-A2 | FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2024-10-24 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |