Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956224 | 0.86 | CA12 (0.60) | CA12CA9ALDH1A1LMNARECQL | |
| SCHEMBL4020469 | 0.83 | CA12 (0.62) | CA12CA9ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29958156 | 0.79 | CYP1A2 (0.49) | ALOX5APFEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL344268 | 0.79 | CYP1A2 (0.49) | ALOX5APFEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1816382 | 0.78 | CA12 (0.50) | CA12CA9ALOX5APFEN1ALDH1A1 | |
| SCHEMBL289765 | 0.77 | PSIP1 (0.45) | CA12CA9ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29670227 | 0.77 | PSIP1 (0.45) | CA12CA9ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL519774 | 0.76 | NSD2 (0.47) | ALOX5APFEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29442141 | 0.76 | NSD2 (0.47) | ALOX5APFEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6034914 | 0.76 | TSHR (0.55) | LMNASMN1; SMN2KDM4EKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |