Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.35 |
| ▸ | PIM1 | P11309 | 4/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957644 | 0.79 | KDM5A (0.41) | AXLPRKCIKMT2ADYRK1ADAO | |
| SCHEMBL29955676 | 0.79 | KMT2A (0.33) | PIM1KMT2ACCR1CCR5CCR8 | |
| SCHEMBL21917254 | 0.77 | AXL (0.43) | AXLPIM1PRKCICLK1GSK3B | |
| SCHEMBL6219703 | 0.72 | AXL (0.40) | AXLPIM3PIM1PRKCICLK1 | |
| SCHEMBL13909727 | 0.69 | PIM3 (0.48) | PIM3PIM1KMT2APIM2CCR1 | |
| SCHEMBL29952712 | 0.69 | PIM3 (0.48) | PIM3PIM1KMT2APIM2CCR1 | |
| SCHEMBL13996388 | 0.68 | AXL (0.41) | AXLPIM3PIM1KMT2APIM2 | |
| SCHEMBL29952576 | 0.67 | — | — | |
| SCHEMBL29936066 | 0.66 | GRM5 (0.40) | AXLCCR1CCR5CCR8CYP2A6 | |
| SCHEMBL29951565 | 0.66 | MAPT (0.44) | PIM3KMT2ACLK1GSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |