Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954069 | 0.79 | AXL (0.40) | KMT2AAXLPRKCIDYRK1ADAO | |
| SCHEMBL29955676 | 0.79 | KMT2A (0.33) | KMT2ACCR1CCR5CCR8TRIM24 | |
| SCHEMBL25910888 | 0.72 | TDO2 (0.33) | DYRK1ATRIM24TRIM33 | |
| SCHEMBL29956271 | 0.70 | TRIM24 (0.49) | KDM5AKDM4CKMT2ACCR1CCR5 | |
| SCHEMBL20125333 | 0.69 | KDM5A (0.55) | KDM5AKDM4CKMT2AAXLPRKCI | |
| SCHEMBL5303261 | 0.67 | ALDH1A1 (0.34) | KMT2AAXLPRKCIKDM4EALDH1A1 | |
| SCHEMBL13909686 | 0.67 | KDM5A (0.45) | KDM5AKDM4CKMT2AAXLPRKCI | |
| SCHEMBL5212066 | 0.66 | ALDH1A1 (0.48) | KMT2AAXLPRKCIKDM4EALDH1A1 | |
| SCHEMBL29936066 | 0.66 | GRM5 (0.40) | AXLCCR1CCR5CCR8 | |
| SCHEMBL29951565 | 0.66 | MAPT (0.44) | KMT2ADYRK1AKDM4ES1PR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |