Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952207 | 0.85 | GAA (0.37) | NPC1GAAENPP2CHEK1SMN1; SMN2 | |
| SCHEMBL19615024 | 0.75 | NPC1 (0.41) | NPC1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29957528 | 0.75 | CD44 (0.32) | ALDH1A1KDM4ECYP3A4RAB9AMEN1 | |
| SCHEMBL20225783 | 0.74 | NPC1 (0.43) | NPC1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14094830 | 0.72 | NPC1 (0.42) | NPC1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28015248 | 0.72 | NPC1 (0.42) | NPC1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL1191784 | 0.72 | ENPP2 (0.39) | NPC1ENPP2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29694733 | 0.72 | ENPP2 (0.39) | NPC1ENPP2SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL22491094 | 0.71 | GAA (0.50) | NPC1GAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL29954133 | 0.71 | CD44 (0.32) | SMN1; SMN2ALDH1A1KDM4ERAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |