Styrene

Styrene

SCHEMBL2995439

C=Cc1ccccc1.CN(C)Cc1ccccc1.[Pd]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
ALDH1A1 P00352 2/20 0.65
TAAR1 Q96RJ0 2/20 0.52
AOC3 Q16853 1/20 0.45
HRH3 Q9Y5N1 1/20 0.43
G6PC1 P35575 2/20 0.43
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNA4 P43681 1/20 0.40
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
HTR2A P28223 1/20 0.39
ADRA1A P35348 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL10628429 0.98 TSHR (0.68) TSHRALDH1A1TAAR1AOC3HRH3
Styrene SCHEMBL28826718 0.92 ALDH1A1 (0.59) TSHRALDH1A1TAAR1AOC3HRH3
Benzene SCHEMBL10537623 0.85 ALDH1A1 (0.54) TSHRALDH1A1TAAR1AOC3HRH3
SCHEMBL465236 0.84 HRH3 (0.56) TSHRALDH1A1TAAR1HRH3CHRNB2
Styrene SCHEMBL8775613 0.83 ALDH1A1 (0.48) TSHRALDH1A1TAAR1AOC3HRH3
Hydrochloric Acid SCHEMBL1396391 0.82 HRH3 (0.54) TSHRALDH1A1TAAR1HRH3CHRNB2
Styrene SCHEMBL27991452 0.82 ALDH1A1 (0.61) TSHRALDH1A1AOC3G6PC1OPRK1
Ethane SCHEMBL6027727 0.82 HRH3 (0.54) TSHRALDH1A1TAAR1HRH3CHRNB2
SCHEMBL10537627 0.81 ALDH1A1 (0.50) TSHRALDH1A1TAAR1AOC3HRH3
Styrene SCHEMBL10628379 0.81 TSHR (0.50) TSHRALDH1A1AOC3G6PC1CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100202950-A1 Method of Preparing Heterogeneous Catalysts NEVEROV ALEXEI A 2010-08-12 US disclosed