Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337440 | 0.85 | KDM4E (0.42) | KDM4EPIK3CDNQO2CNR1CNR2 | |
| SCHEMBL2065172 | 0.82 | KDM4E (0.45) | KDM4EPIK3CDNQO2CNR1CNR2 | |
| SCHEMBL4439323 | 0.82 | KDM4E (0.45) | KDM4EPIK3CDNQO2CNR1CNR2 | |
| SCHEMBL10337812 | 0.81 | KDM4E (0.39) | KDM4EPIK3CDNQO2NAAA | |
| SCHEMBL3020556 | 0.79 | — | — | |
| SCHEMBL4870336 | 0.78 | PIK3CD (0.49) | KDM4EPIK3CDPER2CRY2GRM2 | |
| SCHEMBL1712876 | 0.77 | — | — | |
| SCHEMBL15153625 | 0.77 | KDM4E (0.41) | KDM4EPIK3CDNQO2CNR1CNR2 | |
| SCHEMBL8903181 | 0.76 | KDM4E (0.43) | KDM4EPIK3CDNQO2CNR1CNR2 | |
| SCHEMBL18052333 | 0.76 | KDM4E (0.43) | KDM4EPIK3CDNQO2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |