SCHEMBL29954489

SCHEMBL29954489

CCc1cc(C=O)ccn1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 9/20 0.40
PRKCI P41743 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
FDPS P14324 1/20 0.37
ALDH1A3 P47895 4/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
SREBF1 P36956 1/20 0.36
SREBF2 Q12772 1/20 0.36
ALDH3A1 P30838 3/20 0.35
TSHR P16473 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7424324 1.00 CYP1A2 (0.44) CYP1A2POLBALDH1A1PRKCISMN1; SMN2
SCHEMBL29951723 0.85 KDM4E (0.49) ALDH1A1SMN1; SMN2KDM4EALDH1A3LMNA
SCHEMBL7426398 0.85 KDM4E (0.49) ALDH1A1SMN1; SMN2KDM4EALDH1A3LMNA
SCHEMBL28787234 0.82 KDM4E (0.39) CYP1A2ALDH1A1SMN1; SMN2KDM4EFDPS
SCHEMBL13706049 0.80 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2KDM4EFDPSALDH1A3
SCHEMBL20276120 0.80 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2KDM4EFDPS
SCHEMBL29956230 0.80 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2KDM4EFDPS
SCHEMBL321696 0.80 CYP1A2 (0.44) CYP1A2POLBALDH1A1PRKCIKDM4E
SCHEMBL29955237 0.80 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2KDM4EFDPS
Bromide SCHEMBL28155749 0.78 CYP1A2 (0.43) CYP1A2POLBALDH1A1PRKCIKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed