Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 4/20 | 0.37 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16110848 | 1.00 | CCR1 (0.38) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL29957464 | 0.80 | CCR1 (0.37) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL15573110 | 0.78 | CCR1 (0.35) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL29956787 | 0.78 | NOS2 (0.54) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL29957824 | 0.78 | CYP2A6 (0.32) | CYP2A6 | |
| SCHEMBL29952729 | 0.78 | CCR1 (0.35) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL2371767 | 0.78 | CCR1 (0.35) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL29952668 | 0.78 | CCR1 (0.35) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL16225239 | 0.75 | CCR1 (0.33) | CCR1CCR5CCR8NOS2NOS3 | |
| SCHEMBL22720322 | 0.75 | CCR1 (0.33) | CCR1CCR5CCR8NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116848107-A | Compounds and their use as PDE4 activators | 米罗尼德有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-116194456-A | Preparation of heterocyclic compounds as KRAS inhibitors and methods of use thereof | 上海科州药物研发有限公司 | 2023-05-30 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |