Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478704 | 0.77 | MAPT (0.67) | MAPTCASP1PDGFRBPDGFRAAURKA | |
| SCHEMBL14479730 | 0.77 | MAPT (0.67) | MAPTCASP1PDGFRBPDGFRAAURKA | |
| SCHEMBL27892862 | 0.76 | MAPT (0.65) | MAPTCASP1PDGFRBPDGFRAAURKA | |
| SCHEMBL29954554 | 0.76 | ALDH1A1 (0.51) | MAPTCASP1PDGFRBPDGFRAKMT2A | |
| SCHEMBL5782653 | 0.75 | MAPT (0.59) | MAPTCASP1PDGFRBPDGFRAAURKA | |
| SCHEMBL14931747 | 0.75 | MAPT (0.59) | MAPTCASP1PDGFRBPDGFRAAURKA | |
| SCHEMBL12427762 | 0.75 | MAPT (0.59) | MAPTCASP1PDGFRBPDGFRAAURKA | |
| SCHEMBL2432812 | 0.73 | MAPT (0.61) | MAPTCASP1PDGFRBPDGFRAFYN | |
| SCHEMBL4876885 | 0.73 | AXL (0.59) | MAPTCASP1PDGFRBPDGFRAKMT2A | |
| SCHEMBL1542626 | 0.73 | SLC13A5 (0.38) | MAPTCASP1AURKATTKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |