Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951521 | 1.00 | ERN1 (0.45) | ERN1SLC1A1SRCCNR1CNR2 | |
| SCHEMBL29957454 | 0.88 | ERN1 (0.49) | ERN1SRCMAPTGRK6LMNA | |
| SCHEMBL29952652 | 0.88 | ERN1 (0.49) | ERN1SRCMAPTGRK6LMNA | |
| SCHEMBL29953033 | 0.85 | ERN1 (0.49) | ERN1SLC1A1SRCMAPTGRK6 | |
| SCHEMBL29955683 | 0.85 | ERN1 (0.49) | ERN1SLC1A1SRCMAPTGRK6 | |
| SCHEMBL15331771 | 0.81 | ERN1 (0.53) | ERN1SRCGRK6ALDH1A1 | |
| SCHEMBL15333065 | 0.81 | ERN1 (0.53) | ERN1SRCGRK6ALDH1A1 | |
| SCHEMBL15332204 | 0.81 | ERN1 (0.53) | ERN1SRCMAPTGRK6LMNA | |
| SCHEMBL2561255 | 0.81 | ERN1 (0.53) | ERN1SRCMAPTGRK6LMNA | |
| SCHEMBL29950878 | 0.81 | ERN1 (0.46) | ERN1SRCGRK6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |