Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955683 | 1.00 | ERN1 (0.49) | ERN1SRCGRK6GABRPGABRD | |
| SCHEMBL29952548 | 0.92 | ERN1 (0.46) | ERN1SRCGRK6TSHRTBXA2R | |
| SCHEMBL29950878 | 0.92 | ERN1 (0.46) | ERN1SRCGRK6TSHRTBXA2R | |
| SCHEMBL29951521 | 0.85 | ERN1 (0.45) | ERN1SRCGRK6MEN1KMT2A | |
| SCHEMBL29954587 | 0.85 | ERN1 (0.45) | ERN1SRCGRK6MEN1KMT2A | |
| SCHEMBL15332204 | 0.84 | ERN1 (0.53) | ERN1SRCGRK6MAPT | |
| SCHEMBL15331771 | 0.84 | ERN1 (0.53) | ERN1SRCGRK6PDE5AALDH1A1 | |
| SCHEMBL2561255 | 0.84 | ERN1 (0.53) | ERN1SRCGRK6MAPT | |
| SCHEMBL15333065 | 0.84 | ERN1 (0.53) | ERN1SRCGRK6PDE5AALDH1A1 | |
| SCHEMBL15330741 | 0.82 | ERN1 (0.50) | ERN1SRCGRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |