SCHEMBL29954687

SCHEMBL29954687

OCc1cccc2ccc(B(O)O)cc12

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
ENPP2 Q13822 5/20 0.47
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
MGLL Q99685 1/20 0.36
ACP3 P15309 1/20 0.36
MAPK1 P28482 1/20 0.35
MC5R P33032 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956556 0.86 CA1 (0.50) CA1CA2ENPP2TDP1KDM4E
SCHEMBL29465865 0.79 CA1 (0.65) CA1CA2ENPP2TDP1ALDH1A1
SCHEMBL1527433 0.79 CA1 (0.65) CA1CA2ENPP2TDP1ALDH1A1
SCHEMBL29792638 0.78 CYP2A6 (0.43) TDP1CYP1A2CYP2C9CYP2C19ACP3
SCHEMBL3571906 0.78 CYP2A6 (0.43) TDP1CYP1A2CYP2C9CYP2C19ACP3
SCHEMBL31139487 0.76 CA2 (0.58) CA1CA2ENPP2KDM4EALDH1A1
SCHEMBL3044020 0.76 MAPK1 (0.45) ENPP2TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL31286354 0.76 CA1 (0.61) CA1CA2TDP1ALDH1A1CYP1A2
SCHEMBL30587139 0.76 MAPK1 (0.45) ENPP2TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL29956064 0.76 CA1 (0.55) CA1CA2ENPP2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed