Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.64 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2309341 | 1.00 | CYP2A6 (0.64) | CYP2A6TRIM24TRIM33GPR84IMPDH2 | |
| SCHEMBL27308948 | 0.85 | CYP2A6 (0.54) | CYP2A6TRIM24TRIM33GPR84IMPDH2 | |
| SCHEMBL31279438 | 0.85 | CYP2A6 (0.54) | CYP2A6TRIM24TRIM33GPR84IMPDH2 | |
| SCHEMBL29952428 | 0.82 | CYP2A6 (0.70) | CYP2A6TRIM24TRIM33IMPDH2ALDH1A1 | |
| SCHEMBL1224614 | 0.80 | GPR84 (0.64) | CYP2A6TRIM24TRIM33GPR84ALDH1A1 | |
| SCHEMBL30552280 | 0.80 | GPR84 (0.64) | CYP2A6TRIM24TRIM33GPR84ALDH1A1 | |
| SCHEMBL248842 | 0.79 | CYP2A6 (0.66) | CYP2A6TRIM24TRIM33IMPDH2ALDH1A1 | |
| SCHEMBL29408411 | 0.79 | CYP2A6 (0.66) | CYP2A6TRIM24TRIM33IMPDH2ALDH1A1 | |
| SCHEMBL29952017 | 0.79 | CYP2A6 (0.60) | CYP2A6TRIM24TRIM33GPR84IMPDH2 | |
| SCHEMBL31448009 | 0.78 | GPR84 (0.46) | CYP2A6GPR84ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119330869-A | Indole acrylic amide derivative and preparation method and application thereof | 常州大学 | 2025-01-21 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |