Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 9/20 | 0.51 |
| ▸ | PIM1 | P11309 | 7/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953035 | 0.83 | PIM3 (0.55) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL29952798 | 0.79 | PIM3 (0.50) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL30859480 | 0.79 | PIM3 (0.51) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL29953642 | 0.79 | PIM3 (0.51) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL29957633 | 0.79 | TRIM24 (0.47) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL14519078 | 0.79 | PIM3 (0.65) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL29955386 | 0.77 | TRIM24 (0.66) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL7836451 | 0.76 | CA1 (0.50) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL29952579 | 0.76 | PIM3 (0.48) | PIM3PIM1PIM2CYP2A6TRIM24 | |
| SCHEMBL29955189 | 0.74 | PIM3 (0.50) | PIM3PIM1PIM2CYP2A6TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |