Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 9/20 | 0.47 |
| ▸ | PIM1 | P11309 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835597 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTTRIM24TRIM33 | |
| SCHEMBL29952386 | 0.81 | PIM3 (0.51) | CA1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL29958402 | 0.81 | ALDH1A1 (0.48) | CA1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL29955110 | 0.81 | ALDH1A1 (0.48) | CA1CA2ALDH1A1KDM4EMAPT | |
| SCHEMBL29954723 | 0.76 | PIM3 (0.51) | ALDH1A1KDM4EMAPTTRIM24TRIM33 | |
| SCHEMBL29952798 | 0.76 | PIM3 (0.50) | ALDH1A1KDM4EMAPTTRIM24TRIM33 | |
| SCHEMBL29957633 | 0.76 | TRIM24 (0.47) | ALDH1A1KDM4EMAPTTRIM24TRIM33 | |
| SCHEMBL14519078 | 0.75 | PIM3 (0.65) | ALDH1A1KDM4EMAPTTRIM24TRIM33 | |
| SCHEMBL7836770 | 0.75 | TUBB1 (0.57) | — | |
| SCHEMBL29955386 | 0.73 | TRIM24 (0.66) | CA1CA2TRIM24TRIM33PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680950-B1 | PROPENONE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5952355-A | 1-ETHER-SUBSTITUTED PHENYL-3-INDOL-3-YL-2-PROPEN-1-ONE DERIVATIVES; ANTITUMOR AND -CARCINOGENIC AGENTS; IMMUNOSUPPRESSANTS; AUTOIMMUNE DISEASES; SIDE EFFECT REDUCTION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0680950-A1 | PROPENONE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-11-08 | — | — | EP | disclosed |