Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RPA1 | P27694 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330850 | 0.89 | TRIM24 (0.43) | KDM4ERPA1MCL1KIF11TRIM24 | |
| SCHEMBL5635400 | 0.87 | TNKS (0.43) | KDM4EKIF11TRIM24TRIM33AHR | |
| SCHEMBL15332841 | 0.87 | TNKS2 (0.43) | KDM4ERPA1MCL1KIF11TRIM24 | |
| SCHEMBL15330118 | 0.87 | KDM4E (0.44) | KDM4ERPA1MCL1KIF11TRIM24 | |
| SCHEMBL15331976 | 0.86 | CCNB2 (0.47) | KDM4ERPA1MCL1KIF11TRIM24 | |
| SCHEMBL15332325 | 0.84 | TNKS2 (0.46) | KDM4ERPA1MCL1TRIM24TRIM33 | |
| SCHEMBL15330854 | 0.84 | TRIM24 (0.39) | KDM4ERPA1MCL1KIF11TRIM24 | |
| SCHEMBL15330627 | 0.84 | ALOX5 (0.43) | KDM4ERPA1MCL1KIF11TRIM24 | |
| SCHEMBL15330398 | 0.84 | TRIM24 (0.39) | KDM4ERPA1MCL1KIF11TRIM24 | |
| SCHEMBL15331414 | 0.84 | TRIM24 (0.39) | KDM4ERPA1MCL1KIF11TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |