Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 12/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380412 | 1.00 | ERN1 (0.57) | ERN1CDK1TRIM24TRIM33KDM4E | |
| Hydrochloric Acid SCHEMBL31191963 | 0.98 | ERN1 (0.55) | ERN1CDK1TRIM24TRIM33KDM4E | |
| SCHEMBL29955412 | 0.84 | ERN1 (0.67) | ERN1 | |
| SCHEMBL2558331 | 0.84 | ERN1 (0.67) | ERN1 | |
| 5-Bromosalicylaldehyde SCHEMBL28103357 | 0.82 | ERN1 (0.81) | ERN1CDK1KDM4EALDH1A1ALOX15 | |
| SCHEMBL6029813 | 0.82 | TYR (0.52) | ERN1TRIM24TRIM33KDM4EMEN1 | |
| SCHEMBL2554069 | 0.79 | ERN1 (0.65) | ERN1 | |
| SCHEMBL11664879 | 0.78 | LMNA (0.46) | KDM4EMEN1ALDH1A1CYP3A4THRB | |
| SCHEMBL22630789 | 0.77 | CA1 (0.46) | KDM4EMEN1ALDH1A1TNFCYP3A4 | |
| SCHEMBL3679569 | 0.77 | CA1 (0.46) | KDM4EMEN1ALDH1A1TNFCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |