Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834368 | 0.79 | LMNA (0.47) | CYP2C19CYP2C9L3MBTL1GAALMNA | |
| SCHEMBL2586535 | 0.78 | LMNA (0.46) | CYP2C19CYP2C9L3MBTL1GAALMNA | |
| SCHEMBL3689393 | 0.78 | LMNA (0.46) | CYP2C19CYP2C9L3MBTL1GAALMNA | |
| SCHEMBL2585488 | 0.78 | TSHR (0.46) | CYP2C9L3MBTL1CYP1A2LMNAPOLB | |
| SCHEMBL12636204 | 0.77 | CYP2C19 (0.46) | CYP2C19CYP2C9L3MBTL1GAALMNA | |
| SCHEMBL14488613 | 0.75 | TP53 (0.46) | CYP2C19CYP2C9L3MBTL1LMNAPOLB | |
| SCHEMBL23213616 | 0.74 | POLB (0.57) | L3MBTL1GAALMNAPOLBKDM4E | |
| SCHEMBL30231151 | 0.73 | CYP2C19 (0.49) | CYP2C19CYP2C9L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL24077079 | 0.73 | CYP2C19 (0.49) | CYP2C19CYP2C9L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL12636203 | 0.72 | MAPK14 (0.48) | CYP2C19CYP2C9L3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |