Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.56 |
| ▸ | CMA1 | P23946 | 2/20 | 0.56 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 5/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415750 | 1.00 | AHR (0.56) | AHRCMA1EIF2AK2PDK2CRBN | |
| SCHEMBL14485082 | 0.86 | AHR (0.56) | AHRCMA1EIF2AK2PDK2SMYD3 | |
| SCHEMBL29951659 | 0.86 | AHR (0.56) | AHRCMA1EIF2AK2PDK2SMYD3 | |
| SCHEMBL18094182 | 0.84 | CA9 (0.57) | CRBNSMYD3CA9 | |
| SCHEMBL1833499 | 0.76 | AHR (0.61) | AHRCMA1EIF2AK2PDK2CRBN | |
| SCHEMBL31478025 | 0.76 | AHR (0.61) | AHRCMA1EIF2AK2PDK2CRBN | |
| SCHEMBL1854108 | 0.75 | EIF2AK2 (0.68) | AHRCMA1EIF2AK2PDK2CRBN | |
| SCHEMBL4594796 | 0.74 | NPC1 (0.50) | CRBNSMYD3PDE3BPDE3ACA9 | |
| SCHEMBL426952 | 0.72 | MMP12 (0.61) | SMYD3 | |
| SCHEMBL19042841 | 0.72 | AHR (0.61) | AHRCMA1EIF2AK2PDK2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |