Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954114 | 0.95 | PDE4B (0.51) | ALDH1A1TSHRPDE4BFDPSPDE3A | |
| SCHEMBL28147814 | 0.81 | PTGS1 (0.48) | ALDH1A1PDE4BPDE3APDE4APDE4C | |
| SCHEMBL28844965 | 0.81 | PTGS1 (0.48) | ALDH1A1PDE4BPDE3APDE4APDE4C | |
| SCHEMBL2561769 | 0.80 | ALDH1A1 (0.40) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29956283 | 0.78 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3KDM4EHPGD | |
| SCHEMBL2840516 | 0.77 | ALDH1A1 (0.64) | ALDH1A1TSHRPDE4BFDPSPDE3A | |
| SCHEMBL2847455 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TSHRPDE4BFDPSPDE3A | |
| SCHEMBL2555346 | 0.76 | SRC (0.38) | NPC1TDP1 | |
| SCHEMBL2557305 | 0.75 | SRC (0.43) | ALDH1A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29954512 | 0.74 | SRC (0.37) | ALDH1A1PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |