Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044447 | 0.86 | KMT2A (0.44) | KMT2AMEN1S100A4NPC1RAB9A | |
| SCHEMBL3713256 | 0.84 | TRIM24 (0.47) | TRIM24TRIM33KMT2AMEN1NPC1 | |
| SCHEMBL20805744 | 0.83 | KMT2A (0.42) | KMT2AMEN1S100A4NPC1RAB9A | |
| SCHEMBL1375331 | 0.82 | L3MBTL1 (0.45) | TRIM24TRIM33KMT2AMEN1NPC1 | |
| SCHEMBL9000485 | 0.81 | KMT2A (0.40) | KMT2AMEN1S100A4NPC1RAB9A | |
| SCHEMBL31048761 | 0.81 | CA1 (0.44) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL28110815 | 0.79 | TRIM24 (0.42) | TRIM24TRIM33KMT2AMEN1NPC1 | |
| SCHEMBL306384 | 0.79 | METAP1 (0.44) | TRIM24TRIM33RAB9AHTTL3MBTL1 | |
| SCHEMBL2211898 | 0.79 | CYP1A2 (0.48) | NPC1RAB9AHTTKDM4ECYP1A2 | |
| SCHEMBL31023942 | 0.78 | TRIM24 (0.52) | TRIM24TRIM33KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |