Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595014 | 0.86 | KDM4E (0.42) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL29951090 | 0.81 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL2423817 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL162807 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL3809367 | 0.78 | CYP1A2 (0.53) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL19358702 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL38659549 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL20595215 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL28509975 | 0.77 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDHTTRECQL | |
| SCHEMBL8552985 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |