SCHEMBL29954952

SCHEMBL29954952

CCOc1ccc(B(O)O)s1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
NQO1 P15559 1/20 0.34
ALDH1A1 P00352 1/20 0.31
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29951823 0.82 NR5A1 (0.40) TSHRLTA4H
SCHEMBL8562919 0.78 NQO1 (0.48) TSHRNQO1ALDH1A1LTA4H
SCHEMBL2320027 0.77 TSHR (0.46) TSHR
SCHEMBL15624566 0.72
SCHEMBL826487 0.70
SCHEMBL1959029 0.69 TSHR (0.65) TSHR
SCHEMBL12553160 0.69 TSHR (0.43) TSHR
SCHEMBL6963519 0.68 TSHR (0.46) TSHRALDH1A1
SCHEMBL18067916 0.68 NQO1 (0.39) TSHRNQO1ALDH1A1LTA4H
SCHEMBL12215731 0.68 TSHR (0.42) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed