SCHEMBL29954959

SCHEMBL29954959

OB(O)c1cc(Cl)ncc1F

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNQ3 O43525 7/20 0.33
KCNQ2 O43526 7/20 0.33
KCNE1 P15382 5/20 0.32
KCNQ1 P51787 5/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DAO P14920 1/20 0.30
DDO Q99489 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1192768 1.00 KCNQ3 (0.33) KCNQ3KCNQ2KCNE1KCNQ1SMN1; SMN2
SCHEMBL29953252 0.83 KCNQ3 (0.33) KCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL29514284 0.78 VRK1 (0.32)
SCHEMBL2714951 0.78 MEN1 (0.32)
SCHEMBL1192318 0.78 VRK1 (0.32)
SCHEMBL29951515 0.78 MEN1 (0.32)
SCHEMBL29953715 0.77 ALDH1A1 (0.36) KCNQ3KCNQ2SMN1; SMN2
SCHEMBL29911781 0.77 UHRF1 (0.35) KCNQ3KCNQ2SMN1; SMN2
SCHEMBL29954422 0.77 ERN1 (0.30)
SCHEMBL29950670 0.77 VRK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed