Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23166582 | 0.78 | DYRK1A (0.39) | VCAM1DYRK1ADYRK1BMETKDM4E | |
| SCHEMBL15155057 | 0.78 | JAK2 (0.48) | DYRK1ADYRK1BMET | |
| SCHEMBL15154912 | 0.78 | SMN1; SMN2 (0.44) | DYRK1ADYRK1BMETMAPTLMNA | |
| SCHEMBL7114099 | 0.78 | DYRK1A (0.48) | DYRK1ADYRK1BKMT2AMETALDH1A1 | |
| SCHEMBL24764929 | 0.77 | KMT2A (0.54) | AXLKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL22050731 | 0.75 | JAK2 (0.41) | VCAM1DYRK1ADYRK1BMET | |
| SCHEMBL20292802 | 0.74 | AXL (0.45) | AXLDYRK1ADYRK1BKMT2A | |
| SCHEMBL20319048 | 0.74 | MET (0.44) | AXLKMT2AMET | |
| SCHEMBL22517081 | 0.74 | PRMT5 (0.42) | AXLDYRK1AKMT2A | |
| SCHEMBL18371565 | 0.74 | BTK (0.42) | AXLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |