Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5851624 | 0.88 | MAPT (0.44) | GAAALDH1A1LMNAPGRSMN1; SMN2 | |
| SCHEMBL29952039 | 0.88 | MAPT (0.44) | GAAALDH1A1LMNAPGRSMN1; SMN2 | |
| SCHEMBL29956135 | 0.87 | UTS2R (0.43) | GAAALDH1A1LMNARXFP1BCHE | |
| SCHEMBL29956006 | 0.84 | GAA (0.45) | GAAALDH1A1LMNACA12CA1 | |
| SCHEMBL9986171 | 0.83 | MAPT (0.39) | GAAALDH1A1LMNABCHEACHE | |
| SCHEMBL30716683 | 0.83 | PTGS2 (0.41) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5653976 | 0.83 | PTGS2 (0.41) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29954673 | 0.81 | GAA (0.38) | GAAALDH1A1LMNACA12CA1 | |
| SCHEMBL29955570 | 0.81 | GAA (0.38) | GAAALDH1A1LMNACA12CA1 | |
| SCHEMBL5852069 | 0.80 | PTGS2 (0.41) | GAAALDH1A1LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |