SCHEMBL29955070

SCHEMBL29955070

CC(C)(C)[Si](C)(C)Oc1cncc(B(O)O)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA9 Q16790 4/20 0.35
ENPP2 Q13822 1/20 0.33
PREP P48147 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9988018 0.82 CA1 (0.38) CA12CA1CA9ENPP2PREP
SCHEMBL1881020 0.77 ENPP2 (0.56) CA12CA1CA9ENPP2
SCHEMBL21751355 0.75 CA12 (0.34) CA12CA1CA9ENPP2PREP
SCHEMBL282583 0.75 CA1 (0.50) CA12CA1CA9ENPP2PREP
SCHEMBL17969392 0.75 CA12 (0.38) CA12CA1CA9
SCHEMBL4958 0.74 ENPP2 (0.52) CA1ENPP2
SCHEMBL19782673 0.74 CA12 (0.37) CA12CA1CA9PREP
SCHEMBL201803 0.73
Water SCHEMBL2422179 0.73 ENPP2 (0.50) CA1ENPP2
SCHEMBL932807 0.72 CA1 (0.52) CA12CA1CA9ENPP2PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed