Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956616 | 0.94 | MEN1 (0.41) | MEN1KMT2AALDH1A1TDP1DYRK1A | |
| SCHEMBL29953449 | 0.82 | FEN1 (0.38) | ALDH1A1DYRK1ASLC6A4GSK3BCDK5 | |
| SCHEMBL29956885 | 0.82 | MEN1 (0.32) | MEN1KMT2AALDH1A1TDP1NR3C1 | |
| SCHEMBL29952619 | 0.82 | TRIM24 (0.43) | MEN1KMT2AALDH1A1AHRKDM4E | |
| SCHEMBL29954635 | 0.82 | PIM1 (0.43) | ALDH1A1DYRK1AAHRSLC6A4KDM4E | |
| SCHEMBL29954118 | 0.80 | CHUK (0.35) | MEN1KMT2AALDH1A1TDP1KDM4E | |
| SCHEMBL29953581 | 0.79 | GPR17 (0.36) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL29956762 | 0.78 | PIM1 (0.47) | MEN1KMT2AALDH1A1DYRK1AKDM4E | |
| SCHEMBL29956527 | 0.78 | HTT (0.35) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL29951646 | 0.78 | AR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |