Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952619 | 0.82 | TRIM24 (0.43) | KDM4ECDK1GSK3BCDK5CDK5R1 | |
| SCHEMBL29955079 | 0.82 | MEN1 (0.43) | KDM4ESLC6A4CDK1GSK3BCDK5 | |
| SCHEMBL29953449 | 0.82 | FEN1 (0.38) | SLC6A4GSK3BCDK5CDK5R1DYRK1A | |
| SCHEMBL29956762 | 0.78 | PIM1 (0.47) | PIM1PIM3ENPP3ENPP1KDM4E | |
| SCHEMBL29955208 | 0.78 | ALDH1A1 (0.56) | KDM4EHSD17B10DYRK1ACA12CA9 | |
| SCHEMBL29952127 | 0.78 | — | — | |
| SCHEMBL29951956 | 0.77 | TRIM24 (0.41) | KDM4EDYRK1AAHRALDH1A1 | |
| SCHEMBL29956616 | 0.77 | MEN1 (0.41) | KDM4ESLC6A4CDK1GSK3BCDK5 | |
| SCHEMBL29951772 | 0.77 | DYRK1A (0.40) | SLC6A4GSK3BDYRK1AGSK3A | |
| SCHEMBL7254612 | 0.74 | AHR (0.43) | HSD17B10GSK3BAURKAAHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |