SCHEMBL29955421

SCHEMBL29955421

CSc1cc(F)ccc1B(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37
ADRA2A P08913 2/20 0.34
ADRA2B P18089 2/20 0.34
ADRA2C P18825 2/20 0.34
ADRA1D P25100 2/20 0.34
ADRA1A P35348 2/20 0.34
ADRA1B P35368 2/20 0.34
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33
CA3 P07451 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1359056 1.00 MEN1 (0.37) MEN1MAPTRAB9AKMT2AADRA2A
SCHEMBL2369392 0.83 MEN1 (0.37) MEN1MAPTRAB9AKMT2AADRA2A
SCHEMBL19082496 0.78 KMT2A (0.45) MEN1MAPTRAB9AKMT2AORAI1
SCHEMBL30381395 0.77 MCL1 (0.37) MEN1MAPTKMT2ALMNA
SCHEMBL3786844 0.77 MCL1 (0.37) MEN1MAPTKMT2ALMNA
SCHEMBL30548387 0.75 HPGD (0.42) MEN1MAPTRAB9AKMT2ALMNA
SCHEMBL22411226 0.75 HPGD (0.42) MEN1MAPTRAB9AKMT2ALMNA
SCHEMBL28523649 0.75 TSHR (0.38)
SCHEMBL3791261 0.75 ALDH1A1 (0.38) LMNAKEAP1
SCHEMBL3847009 0.74 MEN1 (0.45) MEN1MAPTRAB9AKMT2AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388560-A1 AROMATIC COMPOUND AND USE THEREOF HITGEN INC (CN) 2025-12-25 US disclosed
EP-4653421-A1 AROMATIC-RING COMPOUND AND USE THEREOF Hitgen Inc. (CN) 2025-11-26 EP disclosed
WO-2024179572-A1 AROMATIC-RING COMPOUND AND USE THEREOF 成都先导药物开发股份有限公司 2024-09-06 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388560-A1 AROMATIC COMPOUND AND USE THEREOF RNF213, RNF10, TRIM4 MEN1 3857/4885MAPT 3041/4885RAB9A 2400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.