Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1226420 | 0.84 | POLB (0.47) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL4104220 | 0.84 | — | — | |
| SCHEMBL15388489 | 0.73 | POLB (0.39) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL17686904 | 0.71 | POLB (0.38) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| SCHEMBL13719910 | 0.70 | POLB (0.39) | POLBTDP1CTDSP1APEX1GRM2 | |
| SCHEMBL25992987 | 0.69 | POLB (0.35) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL1924574 | 0.67 | POLB (1.00) | POLBTDP1CTDSP1APEX1ALDH1A1 | |
| Water SCHEMBL30480124 | 0.67 | POLB (0.33) | POLBTDP1CTDSP1APEX1 | |
| SCHEMBL28340470 | 0.65 | — | — | |
| SCHEMBL25992990 | 0.65 | EGLN1 (0.37) | POLBTDP1CTDSP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |