SCHEMBL1226420

SCHEMBL1226420

O=C(O)C1C=CC(C(=O)O)C=C1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
TDP1 Q9NUW8 3/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
APEX1 P27695 1/20 0.45
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
TSHR P16473 3/20 0.32
LMNA P02545 3/20 0.32
PMP22 Q01453 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
TFPI2 P48307 1/20 0.32
TP53 P04637 1/20 0.32
NFKB1 P19838 1/20 0.32
THPO P40225 1/20 0.32
EDNRA P25101 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
CYP2D6 P10635 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4104220 1.00
SCHEMBL15388489 0.87 POLB (0.39) POLBTDP1CTDSP1APEX1
SCHEMBL29955575 0.84 POLB (0.50) POLBTDP1CTDSP1APEX1LMNA
SCHEMBL17686904 0.84 POLB (0.38) POLBTDP1CTDSP1APEX1CYP2D6
SCHEMBL25992987 0.82 POLB (0.35) POLBTDP1CTDSP1APEX1
Water SCHEMBL30480124 0.79 POLB (0.33) POLBTDP1CTDSP1APEX1
SCHEMBL13719910 0.78 POLB (0.39) POLBTDP1CTDSP1APEX1GRM2
SCHEMBL25992990 0.77 EGLN1 (0.37) POLBTDP1CTDSP1APEX1EGLN1
SCHEMBL28340470 0.77
SCHEMBL17715250 0.75 POLB (0.31) POLBTDP1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3592858-B1 MEANS AND METHODS FOR LIGNIN PYROLYSIS UNIV SAARLAND (DE) 2024-06-12 EP claimed
CN-113651955-A Semi-aromatic polyamide resin with good processability and preparation method and application thereof 中仑塑业(福建)有限公司 2021-11-16 CN claimed
EP-3592858-B1 MEANS AND METHODS FOR LIGNIN PYROLYSIS UNIV SAARLAND (DE) 2024-06-12 EP disclosed
CN-113651955-A Semi-aromatic polyamide resin with good processability and preparation method and application thereof 中仑塑业(福建)有限公司 2021-11-16 CN disclosed
CN-113651955-A Semi-aromatic polyamide resin with good processability and preparation method and application thereof 中仑塑业(福建)有限公司 2021-11-16 CN disclosed
US-20200332320-A1 MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS GENOMATICA, INC. 2020-10-22 US disclosed
US-10415063-B2 Semi-synthetic terephthalic acid via microorganisms that produce muconic acid GENOMATICA, INC. (US) 2019-09-17 US disclosed
US-20190032095-A1 MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS GENOMATICA, INC. 2019-01-31 US disclosed
US-20180312883-A1 SEMI-SYNTHETIC TEREPHTHALIC ACID VIA MICROORGANISMS THAT PRODUCE MUCONIC ACID GENOMATICA, INC. 2018-11-01 US disclosed
US-10059967-B2 Microorganisms and processes for producing terephthalic acid and its salts GENOMATICA, INC. (US) 2018-08-28 US disclosed
US-10041093-B2 Semi-synthetic terephthalic acid via microorganisms that produce muconic acid GENOMATICA, INC. (US) 2018-08-07 US disclosed
US-20060257727-A1 Reactive polymer-supporting porous film for battery seperator and use thereof NITTO DENKO CORPORATION (JP) 2006-11-16 US disclosed
EP-1667253-A1 REACTIVE POLYMER-SUPPORTING POROUS FILM FOR BATTERY SEPARATOR AND USE THEREOF NITTO DENKO CORPORATION (JP) 2006-06-07 EP disclosed
US-6906116-B2 Unsaturated polyester compounds, resins curable with actinic energy ray, processes for the production thereof, and curable compositions KANAGAWA UNIVERSITY (JP) 2005-06-14 US disclosed
US-20050064336-A1 Unsaturated group-containing multi-branched compounds, curable compositions containing the same, and cured products thereof TAIYO INK MANUFACTURING CO., LTD. (JP) 2005-03-24 US disclosed
CN-1498236-A Active energy ray-curable resin and photocurable/thermosetting resin composition containing the same 太阳油墨制造株式会社 2004-05-19 CN disclosed
US-20040039087-A1 Unsaturated polyester compounds, resins curable with actinic energy ray, processes for the production thereof, and curable compositions KANAGAWA UNIVERSITY (JP) 2004-02-26 US disclosed
CN-1109073-C Aromatic polycarbonate resin composition GEN ELECTRIC (US) 2003-05-21 CN disclosed
CN-1223277-A Aromatic polycarbonate resin composition GEN ELECTRIC (US) 1999-07-21 CN disclosed
US-4134850-A CYCLOALIPHATIC PEROXYACIDS GENERATED IN SITU FROM DIACYL PEROXIDE PRECURSORS INTEROX CHEMICALS LIMITED (GB) 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190032095-A1 MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS HPD, PAH, TST POLB 1523/4885TDP1 3218/4885CTDSP1 1091/4885
US-10059967-B2 Microorganisms and processes for producing terephthalic acid and its salts HPD, PAH, TST POLB 1293/4885TDP1 3002/4885CTDSP1 986/4885
US-20200332320-A1 MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS HPD, PAH, TST POLB 1523/4885TDP1 3218/4885CTDSP1 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.