Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.53 |
| ▸ | KLK1 | P06870 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29164290 | 1.00 | CA1 (0.53) | CA1CA2PLGPRSS1F2 | |
| SCHEMBL29957738 | 0.85 | CA1 (0.53) | CA1CA2PLGPRSS1F2 | |
| SCHEMBL31139487 | 0.79 | CA2 (0.58) | CA1CA2ALDH1A1KDM4EENPP2 | |
| SCHEMBL29956064 | 0.78 | CA1 (0.55) | CA1CA2PLAUALDH1A1KDM4E | |
| SCHEMBL1527433 | 0.78 | CA1 (0.65) | CA1CA2ALDH1A1TDP1ENPP2 | |
| SCHEMBL29465865 | 0.78 | CA1 (0.65) | CA1CA2ALDH1A1TDP1ENPP2 | |
| SCHEMBL23581095 | 0.77 | CA1 (0.53) | CA1CA2ALDH1A1KDM4EPOLB | |
| SCHEMBL29955720 | 0.77 | CYP1A2 (0.57) | CA1CA2ALDH1A1KDM4ETDP1 | |
| SCHEMBL5782324 | 0.77 | CA1 (0.53) | CA1CA2ALDH1A1KDM4EKMT2A | |
| SCHEMBL28674038 | 0.77 | CA1 (0.53) | CA1CA2ALDH1A1KDM4EENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |