Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 5/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950806 | 0.86 | KDM4E (0.75) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| Formamide SCHEMBL9731341 | 0.82 | KDM4E (0.42) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL30609119 | 0.82 | KDM4E (0.42) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL9731337 | 0.80 | KDM4E (0.44) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL21625616 | 0.79 | KDM4E (0.75) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL1333120 | 0.77 | KDM4E (0.66) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL30668494 | 0.77 | KDM4E (0.66) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL1025455 | 0.76 | NR4A2 (0.61) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL17028204 | 0.73 | KMT2A (0.49) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL31553579 | 0.73 | CCR1 (0.71) | KDM4EKMT2AL3MBTL1MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |