Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.75 |
| ▸ | NPC1 | O15118 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.75 |
| ▸ | IDO1 | P14902 | 2/20 | 0.75 |
| ▸ | ERN1 | O75460 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM6A | O15550 | 1/20 | 0.47 |
| ▸ | TET3 | O43151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955869 | 0.86 | KDM4E (0.56) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL30080768 | 0.86 | KDM4E (1.00) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL700910 | 0.86 | KDM4E (1.00) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| Formamide SCHEMBL9731188 | 0.82 | KDM4E (0.56) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL9731186 | 0.80 | KDM4E (0.54) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL2011852 | 0.79 | KMT2A (0.56) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL1920452 | 0.78 | KDM4E (0.70) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL27816447 | 0.77 | KDM4E (0.68) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| Methane SCHEMBL27551425 | 0.77 | KDM4E (0.68) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A | |
| SCHEMBL9185003 | 0.76 | KDM4E (0.72) | KDM4EL3MBTL1HSP90AA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |