Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 6/20 | 0.56 |
| ▸ | NOS2 | P35228 | 6/20 | 0.56 |
| ▸ | NOS1 | P29475 | 5/20 | 0.56 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956259 | 0.83 | NOS3 (0.56) | NOS3NOS2NOS1GABRPGABRD | |
| SCHEMBL2766838 | 0.83 | NOS3 (0.56) | NOS3NOS2NOS1GABRPGABRD | |
| SCHEMBL29952665 | 0.78 | GRIA1 (0.44) | NOS3NOS2NOS1GRIA1GRIA2 | |
| SCHEMBL6627536 | 0.78 | GRIA1 (0.44) | NOS3NOS2NOS1GRIA1GRIA2 | |
| SCHEMBL24086660 | 0.75 | GRIA1 (0.37) | NOS3NOS2NOS1GRIA1GRIA2 | |
| SCHEMBL29878553 | 0.75 | CYP1A2 (0.42) | NOS3NOS2NOS1GRIA1GRIA2 | |
| SCHEMBL5118435 | 0.75 | CYP1A2 (0.42) | NOS3NOS2NOS1GRIA1GRIA2 | |
| SCHEMBL29956308 | 0.75 | ERN1 (0.43) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL29957354 | 0.75 | GRIA1 (0.37) | NOS3NOS2NOS1GRIA1GRIA2 | |
| SCHEMBL13699234 | 0.75 | NOS3 (0.35) | NOS3NOS2NOS1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |