Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 6/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 4/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671157 | 0.82 | ERN1 (0.44) | TRIM24TRIM33ERN1PIM3CYP2A6 | |
| SCHEMBL29952505 | 0.79 | TRIM24 (0.40) | TRIM24TRIM33ERN1PIM3CYP2A6 | |
| SCHEMBL29956575 | 0.79 | AR (0.42) | TRIM24TRIM33ERN1PIM3CYP2A6 | |
| SCHEMBL29951658 | 0.79 | PIM3 (0.44) | TRIM24TRIM33ERN1PIM3CYP2A6 | |
| SCHEMBL29955987 | 0.77 | ERN1 (0.47) | TRIM24TRIM33ERN1PIM3CYP2A6 | |
| SCHEMBL29952672 | 0.76 | ALDH1A1 (0.55) | TRIM24TRIM33ERN1PIM3CYP2A6 | |
| SCHEMBL29957147 | 0.72 | CYP2A6 (0.44) | ERN1CYP2A6IMPDH2PLGPLAU | |
| SCHEMBL29950839 | 0.72 | TRIM24 (0.47) | TRIM24TRIM33ERN1PIM3CYP2A6 | |
| SCHEMBL670824 | 0.71 | TRIM24 (0.64) | TRIM24TRIM33PIM3CYP2A6IMPDH2 | |
| SCHEMBL29952475 | 0.70 | ERN1 (0.43) | TRIM24TRIM33ERN1PIM3CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |