Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957588 | 1.00 | HSD17B10 (0.42) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL2552973 | 0.77 | ADRB2 (0.38) | ALDH1A1KCNJ1 | |
| SCHEMBL15330558 | 0.77 | ADRB2 (0.38) | ALDH1A1KCNJ1 | |
| SCHEMBL15329718 | 0.76 | KCNJ1 (0.34) | KCNJ1 | |
| SCHEMBL13049949 | 0.75 | NAPRT (0.48) | HSD17B10TDP1MEN1CYP2C9KMT2A | |
| SCHEMBL2553741 | 0.74 | KCNJ1 (0.35) | KCNJ1 | |
| SCHEMBL15329724 | 0.74 | KCNJ1 (0.35) | KCNJ1 | |
| SCHEMBL15331646 | 0.74 | KCNJ1 (0.35) | KCNJ1 | |
| SCHEMBL15331982 | 0.72 | SLC6A4 (0.41) | SLC6A4KDM4EKCNJ1L3MBTL1 | |
| SCHEMBL15330495 | 0.72 | KCNJ1 (0.34) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |