Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 2/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802409 | 1.00 | POLB (0.44) | POLBTSHRLPLLIPGENPP2 | |
| SCHEMBL1963060 | 0.91 | PDE4A (0.50) | TSHRENPP2KDM4EGAAMAPT | |
| SCHEMBL16426991 | 0.91 | MAPT (0.54) | TSHRENPP2KDM4EGAAMAPT | |
| SCHEMBL3189714 | 0.87 | L3MBTL1 (0.61) | POLBTSHRMAPTALDH1A1LMNA | |
| SCHEMBL2852131 | 0.86 | TSHR (0.38) | POLBTSHRLPLLIPGENPP2 | |
| SCHEMBL16654220 | 0.85 | S1PR1 (0.37) | POLBTSHRLPLLIPGENPP2 | |
| SCHEMBL3659031 | 0.85 | ESR1 (0.46) | TSHRLPLLIPGENPP2KDM4E | |
| SCHEMBL29954924 | 0.85 | ESR1 (0.46) | TSHRLPLLIPGENPP2KDM4E | |
| SCHEMBL3791885 | 0.85 | MAPT (0.47) | POLBLPLLIPGENPP2KDM4E | |
| SCHEMBL1155862 | 0.83 | CA1 (0.46) | LPLLIPGENPP2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |